Category: ESOPHAGUS

Histology Of Esophagus

Histology Of Esophagus

 



 



 

IDENTIFICATION POINTS

  • MUCOSA LINED BY STRATIFIED SQUAMOUS NON-KERATINIZED EPITHELIUM
  • SUB-MUCOSA CONTAINING ESOPHAGEAL GLANDS
  • MUSCULARIS EXTERNA CONTAINING INNER CIRCULAR AND OUTER LONGITUDINAL MUSCLE LAYERS

INTRODUCTION

– EXTENDS FROM LOWER END OF PHARYNX TO CARDIAC END OF STOMACH

– LENGTH: 25cm

– DEVELOPS IN 4th WEEK OF INTRAUTERINE LIFE FROM TRACHEOESOPHAGEAL BUD

STRUCTURE

MUCOSA:

   INNER MOST LAYER OF ESOPHAGUS LINED BY STRATIFIED SQUAMOUS NON-KERATINIZED EPITHELIUM RESTING ON BASEMENT MEMBRANE.SURFACE EPITHELIUM MAY CONTAIN A FEW CELLS BELONGING TO APUD CELL SYSTEM.

 LAMINA PROPRIA:

LOOSE CONNECTIVE TISSUE LAYER BENEATH THE EPITHELIUM ,FOLDED INTO  MANY FINGER LIKE PROJECTIONS CALLED PAPILLAE.

MUSCULARIS MUCOSA/INTERNA:

CONSISTS OF THIN LAYER OF LONGITUDINAL MUSCLE FIBRES.

SUBMUCOSA:

MADE UP OF LOOSE AREOLAR CONNECTIVE TISSUE RICH IN CONNECTIVE TISSUE FIBRES,CELLS AND BLOOD VESSELS. CONSISTS OF COMPUND TUBULO ALVEOLAR MUCOUS GLANDS OR ESOPHAGEAL GLANDS.

MUSCULARIS EXTERNA:

CONSISTS OF OUTER LONGITUDINAL AND INNER CIRCULAR MUSCLE FIBRES.

ADVENTITIA

OUTER MOST PROTECTIVE LAYER MADE UP OF DENSE IRREGULAR CONNECTIVE TISSUE.

CLINICAL

  •       REFLEX ESOPHAGITIS DUE TO REFLUX OF GASTRIC JUICE FROM STOMACH TO LOWER END OF ESOPHAGUS CAUSING DESTRUCTION OF SURFACE EPITHELIUM AND INFLAMMATION.
  •       REPEATED REFLUX ESOPHAGITIS—->COLUMNAR METAPLASIA KNOWN AS BARRETTES ESOPHAGITIS.