Category: GALL BLADDER

HISTOLOGY OF GALL BLADDER

HISTOLOGY OF GALL BLADDER

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IDENTIFICATION POINTS

  • ABSENCE OF SUBMUCOSA AND MUSCULARIS INTERNA.
  • PRESENCE OF FIBRO MUSCULAR COAT.
  • ABSENCE OF GLANDS AND GOBLET CELLS.

INTRODUCTION

– GALL BLADDER IS A MUSCULAR SAC LIKE STRUCTURE SITUATED IN FOSSA OF GALL BLADDER(VISCERAL SURFACE OF LIVER ).

– DIFFERENT PARTS OF GALL BLADDER ARE FUNDUS, BODY AND NECK.

– DEVELOPS IN 4th WEEK OF INTRAUTERINE LIFE FROM ‘PARS CYSTICA’ WHICH IS A PART OF HEPATIC BUD.

STRUCTURE

MUCOSA:

LINED BY SIMPLE COLUMNAR EPITHELIUM WITH FINE MICROVILLI. IT IS HIGHLY FOLDED INTO MANY RUGAE. SUBMUCOSA AND MUSCULARIS MUCOSA ARE ABSENT.

LAMINAPROPRIA:

LOOSE CONNECTIVE TISSUE LAYER BENEATH THE EPITHELIUM.

FIBROMUSCULAR COAT:

CIRCULARLY ARRANGED SMOOTH MUSCLE CELLS WITH FEW ELASTIC FIBRES IN IT.

SEROSA:

MADE UP DENSE IRREGULAR CONNECTIVE TISSUE WITH FEW BLOOD VESSELS IN IT.

FUNCTIONS:

  • STORES BILE.
  • CONCENTRATES THE BILE.
  • DECREASES THE pH OF BILE.
  • CONCENTRATION OF GALL BLADDER MAINTAINS THE PRESSURE IN THE BILLIARY SYSTEM WHICH IS ESSENTIAL FOR THE RELEASE OF BILE INTO SMALL INTESTINE.

CLINICAL:

  • INFLAMMATION OF GALL BLADDER IS CALLED CHOLECYSTITIS.
  • SURGICAL REMOVAL OF GALL BLADDER IS CALLED CHOLECYSTECTOMY.
  • FORMATION OF GALL STONES IN GALL BLADDER RESULTS IN CHOLELITHIASIS.